Mouse CXCL5/LIX/ENA-78/GCP 2 PicoKine® Quick ELISA Kit

SKU: FEK0919

Size: 96 wells/kit, with removable strips.

Storage: Store at 4°C for 6 months. (Ships with gel ice, can store for up to 3 days in room temperature. Refrigerate upon receipt.)

Form:

Reactivity: Mouse

Applications: ELISA

Application Details:

Gene Name: Cxcl5

Specificity: Natural and recombinant mouse Cxcl5

Background: C-X-C motif chemokine 5 is a protein that in humans encoded by the CXCL5 gene. The protein encoded by this gene, CXCL5 is a small cytokine belonging to the CXC chemokine family that is also known as epithelial-derived neutrophil-activating peptide 78 (ENA-78). It is produced following stimulation of cells with the inflammatory cytokines interleukin-1or tumor necrosis factor-alpha. Expression of CXCL5 has also been observed in eosinophils, and can be inhibited with the type II interferon IFN-gamma. This chemokine stimulates the chemotaxis of neutrophils possessing angiogenic properties. It elicits these effects by interacting with the cell surface chemokine receptor CXCR2. The gene for CXCL5 is encoded on four exons and is located on humanchromosome 4 amongst several other CXC chemokine genes. CXCL5 has been implicated in connective tissue remodeling. CXCL5 plays a role in reducing sensitivity to sunburn pain in some subjects, and is a potential target which can be utilized to understand more about pain in other inflammatory conditions like arthritis and cystitis.

Immunogen: Expression system for standard: E.coli; Immunogen sequence: V45-A118

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Uniprot ID: P50228

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 20311

Protein Name: C-X-C motif chemokine 5

Gene Full Name: C-X-C motif chemokine ligand 5

Synonyms: C X C motif chemokine 5; CXCL5; ENA 78; ENA 78(1 78); ENA78; SCYB5; Small inducible cytokine B5