Mouse CXCL4/PF4 ELISA Kit EZ-Set™ (DIY Antibody Pairs)

SKU: EZ0727

Size: 5 plates/kit

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Mouse

Applications: ELISA

Application Details:

Gene Name: Pf4

Specificity: Natural and recombinant mouse CXCL4/PF4

Background: Platelet factor 4 (PF4) is a small cytokine belonging to the CXC chemokine family that is also known as chemokine (C-X-C motif) ligand 4 (CXCL4). The PF4 gene was localized on map to 4q12-q13. Chemokines play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. Platelet factor-4 is a 70-amino acid protein that is released from the alpha-granules of activated platelets and binds with high affinity to heparin. Its major physiologic role appears to be neutralization of heparin-like molecules on the endothelial surface of blood vessels, thereby inhibiting local antithrombin III activity and promoting coagulation. As a strong chemoattractant for neutrophils and fibroblasts, PF4 probably has a role in inflammation and wound repair.

Immunogen: Expression system for standard: E.coli; Immunogen sequence: V30-S105

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Reference:

Uniprot ID: Q9Z126

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 56744

Protein Name: Platelet factor 4

Gene Full Name: platelet factor 4

Synonyms: C X C motif chemokine 4; CXCL4; Iroplact; Oncostatin A; PF 4; PF4; platelet factor 4; SCYB4