Mouse Complement C5,C5 ELISA KIT

SKU: E1797Mo

Size:96 Tests-1 Kit

Background:Activation of C5 by a C5 convertase initiates the spontaneous assembly of the late complement components, C5-C9, into the membrane attack complex. C5b has a transient binding site for C6. The C5b-C6 complex is the foundation upon which the lytic complex is assembled.; Derived from proteolytic degradation of complement C5, C5 anaphylatoxin is a mediator of local inflammatory process. Binding to the receptor C5AR1 induces a variety of responses including intracellular calcium release, contraction of smooth muscle, increased vascular permeability, and histamine release from mast cells and basophilic leukocytes. C5a is also a potent chemokine which stimulates the locomotion of polymorphonuclear leukocytes and directs their migration toward sites of inflammation. {ECO:0000250|UniProtKB:P01031}.

Research_area:

Applications:ELISA

Target_protein:C5

Reactivity:Mouse

Assay type:Sandwich

Sensitivity:0.018ng/ml

Detection range:0.05-15ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Complement 5

Species:Mouse

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P06684

MASS(Da):188878

GeneID:15139

Synonyms:C5 Hc

Gene names:C5

Standard solution:16ng/ml