Mouse cluster of differentiation 44,CD44 ELISA KIT

SKU: E1942Mo

Size:96 Tests-1 Kit

Background:Cell-surface receptor that plays a role in cell-cell interactions, cell adhesion and migration, helping them to sense and respond to changes in the tissue microenvironment. Participates thereby in a wide variety of cellular functions including the activation, recirculation and homing of T-lymphocytes, hematopoiesis, inflammation and response to bacterial infection. Engages, through its ectodomain, extracellular matrix components such as hyaluronan/HA, collagen, growth factors, cytokines or proteases and serves as a platform for signal transduction by assembling, via its cytoplasmic domain, protein complexes containing receptor kinases and membrane proteases (PubMed:8343954, PubMed:25065622). Such effectors include PKN2, the RhoGTPases RAC1 and RHOA, Rho-kinases and phospholipase C that coordinate signaling pathways promoting calcium mobilization and actin-mediated cytoskeleton reorganization essential for cell migration and adhesion (By similarity). {ECO:0000250|UniProtKB:P16070, ECO:0000269|PubMed:25065622, ECO:0000269|PubMed:8343954}.

Research_area:

Applications:ELISA

Target_protein:Cd44

Reactivity:Mouse

Assay type:Sandwich

Sensitivity:0.018ng/mL

Detection range:0.03-9ng/mL

Sample type:Serum, plasma or other biological fluids

Full product name:cluster of differentiation 44

Species:Mouse

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P15379

MASS(Da):85617

GeneID:12505

Synonyms:Cd44 Ly-24

Gene names:Cd44

Standard solution:9.6ng/mL