Mouse Chordin ELISA Kit PicoKine®

SKU: EK1401

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Mouse

Applications: ELISA

Application Details:

Gene Name: Chrd

Specificity: Natural and recombinant mouse Chordin

Background: Chordin is a key developmental protein that dorsalizes early vertebrate embryonic tissues by binding to ventralizing TGF-beta-like bone morphogenetic proteins (BMPs) and sequestering them in latent complexes. In mice, Chordin is expressed in the node but not in the anterior visceral endoderm. It has been found to be required for forebrain development. In developing mice that are deficient in both chordin and noggin, the head is nearly absent. This is significant because when only noggin is deficient there are mild defects but the head still forms. Chordin is also involved in avian gastrulation. It is expressed in the anterior cells of Koller's sickle, which form the anterior cells of the primitive streak, a key structure through which gastrulation occurs.

Immunogen: Expression system for standard: NS0; Immunogen sequence: T27-S948

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Reference:

Uniprot ID: Q9Z0E2

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 12667

Protein Name: Chordin

Gene Full Name: chordin

Synonyms: Chordin; CHRD; UNQ217/PRO243