Mouse Cd9 Antigen, CD9 ELISA Kit

SKU: E1924Mo

Size:96 Tests-1 Kit

Background:Integral membrane protein associated with integrins, which regulates different processes, such as sperm-egg fusion, platelet activation and aggregation, and cell adhesion (PubMed:10700183, PubMed:10634790, PubMed:10634791, PubMed:14715942). Present at the cell surface of oocytes and plays a key role in sperm-egg fusion, possibly by organizing multiprotein complexes and the morphology of the membrane required for the fusion (PubMed:10700183, PubMed:10634790, PubMed:10634791, PubMed:21690351). In myoblasts, associates with CD81 and PTGFRN and inhibits myotube fusion during muscle regeneration (PubMed:23575678). In macrophages, associates with CD9 and beta-1 and beta-2 integrins, and prevents macrophage fusion into multinucleated giant cells specialized in ingesting complement-opsonized large particles. Also prevents the fusion between mononuclear cell progenitors into osteoclasts in charge of bone resorption (PubMed:12796480). Acts as a receptor for PSG17 (PubMed:11805154). Involved in platelet activation and aggregation (PubMed:14715942). Regulates paranodal junction formation (PubMed:14715942). Involved in cell adhesion, cell motility and tumor metastasis (By similarity). Also regulates integrin-dependent migration of macrophages, particularly relevant for inflammatory response in the lung (PubMed:18662991).

Research_area:Immunology

Applications:ELISA

Target_protein:CD9

Reactivity:Mouse

Assay type:Sandwich

Sensitivity:1.27ng/L

Detection range:2-600ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:CD9 antigen

Species:Mouse

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P40240

MASS(Da):25,258

GeneID:12527

Synonyms:CD antigen CD9;CD9;CD9 antigen;Tsp;Tspan29

Gene names:Cd9

Standard solution:640ng/L