Mouse CD44 EZ-Set™ ELISA Kit (DIY Antibody Pairs)

SKU: EZ1419

Size: 5 plates/kit

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Mouse

Applications: ELISA

Application Details:

Gene Name: Cd44

Specificity: Natural and recombinant mouse CD44

Background: CD44 is an integral cell membrane glycoprotein with a postulated role in matrix adhesion lymphocyte activation and lymph node homing. It is contains 19 exons spanning 50 kb of genomic DNA. In humans, the CD44 antigen is encoded by the CD44 gene on Chromosome 11. The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis.

Immunogen: Expression system for standard: CHO; Immunogen sequence: Q25-T224

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Reference:

Uniprot ID: P15379

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 12505

Protein Name: CD44 antigen

Gene Full Name: CD44 antigen

Synonyms: CD44; CD44 antigen; CDW44; CSPG8; ECMR III; Epican; HCELL; Heparan sulfate proteoglycan; Hermes antigen; HUTCH I; Hyaluronate receptor; IN; MC56; MDU2; MDU3; MIC4; MUTCH I; PGP 1; PGP I; Pgp1; Phagocytic glycoprotein 1; Phagocytic glycoprotein I