Mouse Catestatin ELISA Kit

SKU: E1910Mo

Size:96 Tests-1 Kit

Background:Strongly inhibits glucose induced insulin release from the pancreas. Inhibits catecholamine release from chromaffin cells and noradrenergic neurons by acting as a non-competitive nicotinic cholinergic antagonist. Can induce mast cell migration, degranulation and production of cytokines and chemokines. Regulates granule biogenesis in endocrine cells by up-regulating the transcription of protease nexin 1 (SERPINE2) via a cAMP-PKA-SP1 pathway. This leads to inhibition of granule protein degradation in the Golgi complex which in turn promotes granule formation (PubMed:21436258). Pyroglutaminated (pGlu)-serpinin exerts an antiapoptotic effect on cells exposed to oxidative stress (PubMed:21537909).

Research_area:Neuroscience

Applications:ELISA

Target_protein:catestatin

Reactivity:Mouse

Assay type:Sandwich

Sensitivity:14.96ng/L

Detection range:30-9000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:catestatin

Species:Mouse

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P26339

MASS(Da):51,789

GeneID:12652

Synonyms:AL26;Beta-granin;Catestatin;cgA;Ch;ChrA;Chromogranin-A;GE-25;Pancreastatin;p-Glu serpinin precursor];Serpinin;Serpinin-RRG;WE-14;

Gene names:Chga

Standard solution:9600ng/L