Mouse Autophagy Related Protein 4A, ATG4A ELISA Kit

SKU: E2635Mo

Size:96 Tests-1 Kit

Background:Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Preferred substrate is GABARAPL2 followed by MAP1LC3A and GABARAP. Has also an activity of delipidating enzyme for the PE-conjugated forms (By similarity).

Research_area:Cancer

Applications:ELISA

Target_protein:ATG4A

Reactivity:Mouse

Assay type:Sandwich

Sensitivity:12.58ng/L

Detection range:20-6000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Autophagy related protein 4A

Species:Mouse

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q8C9S8

MASS(Da):45,095

GeneID:666468

Synonyms:AI627006;Ap;Apg4a;ATG4A;Atg4al;Aut;Autl2;AUT-like 2 cysteine endopeptidase;Autophagin-2;Autophagy-related cysteine endopeptidase 2;Autophagy-related protein 4 homolog A;Cysteine protease ATG4A

Gene names:Atg4a

Standard solution:8000ng/L