MMP14 Polyclonal Antibody

SKU: E-AB-14218

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: MMP14

Target Synonym: Matrix metallopeptidase 14 (membrane inserted);Matrix metalloproteinase 14;Matrix metalloproteinase-14;Membrane type 1 matrix metalloproteinase;Membrane type 1 metalloprotease;Membrane type matrix metalloproteinase 1;Membrane-type matrix metalloproteinase 1;Membrane-type-1 matrix metalloproteinase;MMP 14;MMP X1;MMP-14;MMP-X1;Mmp14;MMP14;MMPX1;MT MMP 1;MT-MMP 1;MT1 MMP;MT1-MMP;MT1MMP;MTMMP 1;MTMMP1

Research Areas: Cancer;Cell Biology;Cardiovascular;Metabolism;Signal Transduction

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human;Mouse;Rat

Application: IHC

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: P50281

Accession:

Background: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 protein, and this activity may be involved in tumor invasion.

Concentration: 0.4 mg/mL

Immunogen: Recombinant protein of human MMP14

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Dilution: IHC 1:50-1:200

Calculated MW:

ObservedMW: