MMP13 antibody , Cat. # FNab05235

SKU: FNab05235

Size:100ug

Purification:Immunogen affinity purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Rabbit

Clonality:polyclonal

Clone ID:

Isotype:IgG

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:Plays a role in the degradation of extracellular matrix proteins including fibrillar collagen, fibronectin, TNC and ACAN. Cleaves triple helical collagens, including type I, type II and type III collagen, but has the highest activity with soluble type II collagen. Can also degrade collagen type IV, type XIV and type X. May also function by activating or degrading key regulatory proteins, such as TGFB1 and CTGF. Plays a role in wound healing, tissue remodeling, cartilage degradation, bone development, bone mineralization and ossification. Plays a role in keratinocyte migration during wound healing. May play a role in cell migration and in tumor cell invasion.It can detect the glycosylated proMMP-13(70 kDa), unglycosylated proform(54 kDa).

Immunogen:matrix metallopeptidase 13(collagenase 3)

Synonyms:CLG3, Collagenase 3, Matrix metalloproteinase 13, MMP 13, MMP13

Observed MW:54kd,70kd

Uniprot ID:P45452

Reactivity:Human, Mouse, Rat

Tested Application:ELISA, IHC, WB, IF

Recommended dilution:WB: 1:500-1:1000; IHC: 1:20-1:200; IF: 1:10-1:100

Gene ID:4322

Research Area:Stem Cells, Cardiovascular, Metabolism