MLH1 Monoclonal Antibody

SKU: BT-MCA0886

Size:100μL

Background:This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+phenotype) found in HNPCC. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described, but their full-length natures have not been determined.

Research_area:Epigenetics and nuclear signaling; Cancer

Target_protein:MLH1

applications:WB, IHC-p, IF, ICC, ELISA

Reactivity:Human,Monkey

Clonality:Monoclonal

Clone ID:

Host:Mouse

Isotype:IgG

Gene Symbol/ Name:DNA mismatch repair protein Mlh1

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):N/A

UniProt accession:Human: P40692; Mouse: Q9JK91

Synonyms:MLH1; COCA2; DNA mismatch repair protein Mlh1; MutL protein homolog 1

GeneID:Human: 4292