MKK7(Phospho-Ser271/Thr275) Rabbit Polyclonal Antibody

SKU: BT-AP03618

Size:100μL

Background:The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically activates MAPK8/JNK1 and MAPK9/JNK2| and this kinase itself is phosphorylated and activated by MAP kinase kinase kinases including MAP3K1/MEKK1| MAP3K2/MEKK2|MAP3K3/MEKK5| and MAP4K2/GCK. This kinase is involved in the signal transduction mediating the cell responses to proinflammatory cytokines| and environmental stresses. Alternative splicing results in multiple transcript variants.

Research_area:Immunology; Metabolism; Signal transduction

Target_protein:MAP2K7

applications:WB

Reactivity:Human, Rat, Mouse

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:MKK7

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):

UniProt accession:Human: O14733; Mouse: Q8CE90; Rat: Q4KSH7

Synonyms:MKK7 ;Ser271/Thr275; Dual specificity mitogen-activated protein kinase kinase 7; MAP kinase kinase 7; MAPKK 7; EC 2.7.12.2; JNK-activating kinase 2; MAPK/ERK kinase 7; MEK 7; Stress-activated protein kinase kinase 4; SAPK kinase 4; SAPKK-4; SAPKK4; c-Jun N-terminal kinase kinase 2; JNK kinase 2; JNKK 2

GeneID:Human: 5609; Mouse: 26400; Rat: 363855