MEP1B Antibody - Cat. #: CSB-PA618098ESR1HU

SKU: CSB-PA618098ESR1HU

Size :50ul

Clone Number:

Aliases:Endopeptidase 2 antibody; Endopeptidase-2 antibody; kinase splitting membranal proteinase antibody; KSMP antibody; Mep1b antibody; MEP1B_HUMAN antibody; Meprin 1 beta subunit antibody; Meprin A beta antibody; Meprin A beta subunit precursor antibody; Meprin A subunit beta antibody; Meprin B antibody; N benzoyl L tyrosyl P amino benzoic acid hydrolase beta subunit antibody; N-benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit beta antibody; PABA peptide hydrolase antibody; PPH beta antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q16820

Immunogen:Recombinant Human Meprin A subunit beta protein (480-652AA)

Raised in:Rabbit

Species Reactivity:Human, Mouse

Tested Applications:ELISA, WB, IHC; Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200

Background:Membrane metallopeptidase that sheds many membrane-bound proteins. Exhibits a strong preference for acidic amino acids at the P1\\\' position. Known substrates include: FGF19, VGFA, IL1B, IL18, procollagen I and III, E-cadherin, KLK7, gastrin, ADAM10, tenascin-C. The presence of several pro-inflammatory cytokine among substrates implicate MEP1B in inflammation. It is also involved in tissue remodeling due to its capability to degrade extracellular matrix components.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen Affinity Purified

Conjugate:Non-conjugated

Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:MEP1B

Research Areas:Cell biology