MECP2 Antibody - Cat. #: CSB-PA440474

SKU: CSB-PA440474

Size :50ul

Clone Number:

Aliases:AUTSX 3 antibody; AUTSX3 antibody; DKFZp686A24160 antibody; Mbd 5 antibody; Mbd5 antibody; MECP 2 antibody; MeCP 2 protein antibody; MeCP-2 protein antibody; Mecp2 antibody; MECP2_HUMAN antibody; Methyl CpG binding protein 2 (Rett syndrome) antibody; Methyl CpG binding protein 2 antibody; Methyl-CpG-binding protein 2 antibody; MRX 16 antibody; MRX 79 antibody; MRX16 antibody; MRX79 antibody; MRXS 13 antibody; MRXS13 antibody; MRXSL antibody; PPMX antibody; RS antibody; RTS antibody; RTT antibody; WBP 10 antibody; WBP10 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P51608

Immunogen:Fusion protein of Human MECP2

Raised in:Rabbit

Species Reactivity:Human, Mouse, Rat

Tested Applications:ELISA, WB, IHC; ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:100-1:300

Background:DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. MECP2, MBD1 and MBD2 can also repress transcription from methylated gene promoters. In contrast to other MBD family members, MECP2 is X-linked and subject to X inactivation. MECP2 is dispensible in stem cells, but is essential for embryonic development.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:MECP2

Research Areas:Epigenetics and Nuclear Signaling?Neuroscience