MCM2 antibody , Cat. # FNab05057

SKU: FNab05057

Size:100ug

Purification:Protein A+G purification

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Mouse

Clonality:monoclonal

Clone ID:4E3

Isotype:IgG2a

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:Acts as component of the MCM2-7 complex(MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. Required for the entry in S phase and for cell division.

Immunogen:minichromosome maintenance complex component 2

Synonyms:BM28, CCNL1, CDCL1, KIAA0030

Observed MW:116-125 kDa

Uniprot ID:P49736

Reactivity:Human

Tested Application:ELISA, WB

Recommended dilution:WB: 1:1000-1:2000

Gene ID:4171

Research Area:Epigenetics, Cancer, Immunology, Metabolism