MBL2/MBP-C Polyclonal Antibody

SKU: D-AB-10438L

Size::25μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Polyclonal Antibodies

Abbreviation:MBL2/MBP-C

Target Synonym:COLEC1;COLEC1;Collectin-1;HSMBPC;Lectin;mannose-binding;soluble;2;Mannan binding lectin;Mannan binding protein;Mannan-binding protein;Mannose binding lectin (protein C) 2 soluble;Mannose binding lectin (protein C) 2;soluble (opsonic defect);Mannose binding lectin (protein C) 2;soluble;Mannose binding lectin 2 soluble;Mannose binding lectin 2;soluble (opsonic defect);Mannose binding lectin;Mannose binding lectin protein C2 soluble opsonic defect;Mannose binding protein;Mannose binding protein C;Mannose binding protein C precursor;Mannose binding protein;serum;Mannose-binding lectin;Mannose-binding protein C;MBL 2;MBL;MBL2;MBL2;MBL2D;MBP 1;MBP;MBP C;MBP-C;MBP1;MBPB;MBPC;MBPD;MGC116832;MGC116833;Opsonic defect;protein C;Soluble mannose binding lectin

Research Areas:Cancer;Immunology

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:WB

Isotype:IgG

Clonality:Polyclonal

Clone NO.:

UNIProt ID:P11226

Accession:

Background:Mannose-binding Lectin (MBL) is an acute phase protein bearing to the family of collectins produced by the liver as a monomer that forms a triple helix. Once released in serum,it further polymerizes forming dimers to octamers. The degree of serum polymerization is critical for the biological activity of MBL. MBL has higher affinity to microbial polysaccharides or their glycoconjugates. MBL was shown earlier to bind cell surfaces of bacteria,fungi,protozoa and viruses and acts as an acute-phase plasma protein (APP) during infection and inflammation. MBL activates the lectin-complement pathway,promotes opsonophagocytosis and modulates inflammation.

Concentration:1 mg/mL

Immunogen:Recombinant Human MBL2/MBP-C protein expressed by E.coli

Buffer:PBS with 0.02% sodium azide,1% protective protein and 50% glycerol,pH7.4

Purification method:Antigen Affinity Purification

Dilution:WB 1:500-1:1000

Calculated MW:26 kDa

ObservedMW:26 kDa