MARCH8 antibody , Cat. # FNab05004

SKU: FNab05004

Size:100ug

Purification:Immunogen affinity purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Rabbit

Clonality:polyclonal

Clone ID:

Isotype:IgG

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:E3 ubiquitin-protein ligase that mediates ubiquitination of CD86 and MHC class II proteins, such as HLA-DR alpha and beta, and promotes their subsequent endocytosis and sorting to lysosomes via multivesicular bodies. May also promote ubiquitination and endocytosis of TFRC and FAS.

Immunogen:membrane-associated ring finger(C3HC4) 8

Synonyms:MIR, RNF178

Observed MW:33kd

Uniprot ID:Q5T0T0

Reactivity:Human, Mouse

Tested Application:ELISA, WB, IP

Recommended dilution:WB: 1:500-1:1000; IP: 1:200-1:1000

Gene ID:220972

Research Area:Signal Transduction, Metabolism