MARCH4 Antibody - Cat. #: CSB-PA973628

SKU: CSB-PA973628

Size :100ul

Clone Number:

Aliases:MARCHF4 antibody; KIAA1399 antibody; MARCH4 antibody; RNF174E3 ubiquitin-protein ligase MARCHF4 antibody; EC 2.3.2.27 antibody; Membrane-associated RING finger protein 4 antibody; Membrane-associated RING-CH protein IV antibody; MARCH-IV antibody; RING finger protein 174 antibody; RING-type E3 ubiquitin transferase MARCHF4 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q9P2E8

Immunogen:Synthesized peptide derived from internal of Human MARCH4.

Raised in:Rabbit

Species Reactivity:Human, Mouse

Tested Applications:ELISA, IHC; IHC:1:50-1:100

Background:

E3 ubiquitin-protein ligase that may mediate ubiquitination of MHC-I and CD4, and promote their subsequent endocytosis and sorting to lysosomes via multivesicular bodies. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.

Nagase T., DNA Res. 7:65-73(2000).
The MGC Project Team; Genome Res. 14:2121-2127(2004).
Bartee E., J. Virol. 78:1109-1120(2004).

Clonality:Polyclonal

Isotype:IgG

Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Conjugate:Non-conjugated

Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:MARCH4

Research Areas:Cell biology