MADCAM1 Antibody - Cat. #: CSB-RA215817A0HU

SKU: CSB-RA215817A0HU

Size :50ul

Clone Number:12B5

Aliases:Mucosal addressin cell adhesion molecule 1 (MAdCAM-1) (hMAdCAM-1), MADCAM1

Product Type:Recombinant Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q13477

Immunogen:A synthesized peptide derived from human MADCAM1

Raised in:

Species Reactivity:Human

Tested Applications:ELISA, FC; Recommended dilution: FC:1:50-1:200

Background:Cell adhesion leukocyte receptor expressed by mucosal venules, helps to direct lymphocyte traffic into mucosal tissues including the Peyer patches and the intestinal lamina propria. It can bind both integrin alpha-4/beta-7 and L-selectin, regulating both the passage and retention of leukocytes. Isoform 2, lacking the mucin-like domain, may be specialized in supporting integrin alpha-4/beta-7-dependent adhesion strengthening, independent of L-selectin binding.

Clonality:Monoclonal

Isotype:Rabbit IgG

Purification Method:Affinity-chromatography

Conjugate:Non-conjugated

Buffer:Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:MADCAM1

Research Areas:Neuroscience; Cardiovascular; Immunology; Signal transduction