LRSAM1 Antibody - Cat. #: CSB-PA751010ESR1HU

SKU: CSB-PA751010ESR1HU

Size :50ul

Clone Number:

Aliases:CMT2P antibody; E3 ubiquitin protein ligase LRSAM1 antibody; E3 ubiquitin-protein ligase LRSAM1 antibody; EC 6.3.2.- antibody; FLJ31641 antibody; hTAL antibody; Leucine rich repeat and sterile alpha motif containing 1 antibody; Leucine rich repeat and sterile alpha motif containing protein 1 antibody; Leucine-rich repeat and sterile alpha motif-containing protein 1 antibody; LRSAM1 antibody; LRSM1_HUMAN antibody; OTTHUMP00000022174 antibody; OTTHUMP00000022175 antibody; RIFLE antibody; TAL antibody; Tsg101 associated ligase antibody; Tsg101-associated ligase antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q6UWE0

Immunogen:Recombinant Human E3 ubiquitin-protein ligase LRSAM1 protein (1-290AA)

Raised in:Rabbit

Species Reactivity:Human, Mouse

Tested Applications:ELISA, WB, IHC; Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200

Background:E3 ubiquitin-protein ligase that mediates monoubiquitination of TSG101 at multiple sites, leading to inactivate the ability of TSG101 to sort endocytic (EGF receptors) and exocytic (HIV-1 viral proteins) cargos (PubMed:15256501). Bacterial recognition protein that defends the cytoplasm from invasive pathogens (PubMed:23245322). Localizes to several intracellular bacterial pathogens and generates the bacteria-associated ubiquitin signal leading to autophagy-mediated intracellular bacteria degradation (xenophagy) (PubMed:23245322, PubMed:25484098).

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen Affinity Purified

Conjugate:Non-conjugated

Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:LRSAM1

Research Areas:Cell biology; Signal transduction