LRPPRC Antibody, Biotin conjugated - Cat. #: CSB-PA013105LD01HU

SKU: CSB-PA013105LD01HU

Size :50ug

Clone Number:

Aliases:130 kDa leucine-rich protein antibody; gp130 antibody; Leucine-rich PPR motif-containing protein antibody; Leucine-rich PPR-motif containing protein antibody; LPPRC_HUMAN antibody; LRP 130 antibody; lrpprc antibody; mitochondrial antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P42704

Immunogen:Recombinant Human Leucine-rich PPR motif-containing protein, mitochondrial protein (901-1036AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA

Background:May play a role in RNA metabolism in both nuclei and mitochondria. In the nucleus binds to HNRPA1-associated poly(A) mRNAs and is part of nmRNP complexes at late stages of mRNA maturation which are possibly associated with nuclear mRNA export. May bind mature mRNA in the nucleus outer membrane. In mitochondria binds to poly(A) mRNA. Plays a role in translation or stability of mitochondrially encoded cytochrome c oxidase (COX) subunits. May be involved in transcription regulation. Cooperates with PPARGC1A to regulate certain mitochondrially encoded genes and gluconeogenic genes and may regulate docking of PPARGC1A to transcription factors. Seems to be involved in the transcription regulation of the multidrug-related genes MDR1 and MVP. Part of a nuclear factor that binds to the invMED1 element of MDR1 and MVP gene promoters. Binds single-stranded DNA (By similarity).

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:Biotin

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:LRPPRC

Research Areas:Epigenetics and Nuclear Signaling; Neuroscience