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GeneBio Systems

LRPAP1 Polyclonal Antibody

LRPAP1 Polyclonal Antibody

E-AB-12548

¥62,100 JPY
¥62,100 JPY
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Size::120μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Polyclonal Antibodies

Abbreviation:LRPAP1

Target Synonym:39 kDa receptor-associated protein;A2MRAP;A2RAP;Alpha 2 macroglobulin receptor associated protein;Alpha 2 MRAP;Alpha-2-macroglobulin receptor-associated protein;Alpha-2-MRAP;AMRP;HBP44;Lipoprotein receptor associated protein;Low density lipoprotein receptor related protein associated protein 1;Low density lipoprotein receptor-related protein-associated protein 1;Low density lipoprotein related protein associated protein 1 alpha 2 macroglobulin receptor associated protein;Low density lipoprotein related protein associated protein 1;low density lipoprotein-related protein-associated protein 1 (alpha-2-macroglobulin receptor-associated protein 1);Lrpap1;MGC138272;MRAP;MYP23;RAP

Research Areas:Cancer;Cardiovascular;Metabolism;Signal Transduction

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:WB;IHC

Isotype:IgG

Clonality:Polyclonal

Clone NO.:

UNIProt ID:P30533

Accession:

Background:Low density lipoprotein receptor-related protein associated protein 1also known asLRPAP1orRAPis a chaperoneproteinwhich in humans is encoded by the LRPAP1gene. LRPAP1 is involved with trafficking of certain members of the LDL receptor family including LRP1 and LRP2. It is a glycoprotein that binds to the alpha-2-macroglobulin receptor, as well as to other members of the low density lipoprotein receptor family. It acts to inhibit the binding of all know ligands for these receptors, and may prevent receptor aggregation and degradation in the endoplasmic reticulum, thereby acting as a molecular chaperone. It may be under the regulatory control of calmodulin, since it is able to bind calmodulin and be phosphorylated by calmodulin-dependent kinase II.

Concentration:1 mg/mL

Immunogen:Synthetic peptide of human LRPAP1

Buffer:PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method:Affinity purification

Dilution:WB 1:500-1:2000;IHC 1:50-1:200

Calculated MW:41kDa

ObservedMW:

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