LOST1 rabbit pAb

SKU: ES5621

Size: 100μL

Source:Rabbit

Applications:WB;ELISA;IHC

Reactivity:Human;Rat;Mouse;

Dilution:WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000

Immunogen:The antiserum was produced against synthesized peptide derived from human TUSC5. AA range:1-50

Storage_stability:-20°C/1 year

Clonality:Polyclonal

Isotype:IgG

Concentration:1 mg/ml

Observed_band(KD):22kD

Human_gene_id:286753

Human_swiss_prot_no:Q8IXB3

Subcellular_location:Cell membrane ; Single-pass membrane protein . Endomembrane system ; Single-pass membrane protein . Cytoplasm, perinuclear region . Shifts from low-density microsome vesicles to the cell membrane upon insulin stimulation. .

Other_name:TUSC5; IFITMD3; LOST1; Tumor suppressor candidate 5; Dispanin subfamily B member 1; DSPB1; Interferon-induced transmembrane domain-containing protein D3; Protein located at seventeen-p-thirteen point three 1

Background:developmental stage:Expressed in fetal brain.,function:May be involved in fat metabolism.,similarity:Belongs to the CD225 family.,tissue specificity:Expressed at high levels in heart, mammary gland, adrenal gland, stomach, smooth muscle and skeletal muscle, and at lower levels in brain and lung. Strongly down-regulated in lung cancer tissues, due to hypermethylation of the corresponding locus.,