LNX1 antibody , Cat. # FNab04814

SKU: FNab04814

Size:100ug

Purification:Immunogen affinity purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Rabbit

Clonality:polyclonal

Clone ID:

Isotype:IgG

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of NUMB. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates ubiquitination of isoform p66 and isoform p72 of NUMB, but not that of isoform p71 or isoform p65(By similarity). Isoform 2 provides an endocytic scaffold for IGSF5/JAM4.

Immunogen:ligand of numb-protein X 1

Synonyms:LNX, PDZRN2

Observed MW:70 kDa

Uniprot ID:Q8TBB1

Reactivity:Human, Mouse, Rat

Tested Application:ELISA, WB

Recommended dilution: WB: 1:500-1:2000

Gene ID:84708

Research Area:Epigenetics, Metabolism