LMX1B rabbit pAb

SKU: ES6126

Size: 100μL

Source:Rabbit

Applications:WB;IHC;IF;ELISA

Reactivity:Human;Mouse

Dilution:Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.

Immunogen:The antiserum was produced against synthesized peptide derived from human LMX1B. AA range:126-175

Storage_stability:-20°C/1 year

Clonality:Polyclonal

Isotype:IgG

Concentration:1 mg/ml

Observed_band(KD):40kD

Human_gene_id:4010

Human_swiss_prot_no:O60663

Subcellular_location:Nucleus .

Other_name:LMX1B; LIM homeobox transcription factor 1-beta; LIM/homeobox protein 1.2; LMX-1.2; LIM/homeobox protein LMX1B

Background:LIM homeobox transcription factor 1 beta(LMX1B) Homo sapiens This gene encodes a member of LIM-homeodomain family of proteins containing two N-terminal zinc-binding LIM domains, 1 homeodomain, and a C-terminal glutamine-rich domain. It functions as a transcription factor, and is essential for the normal development of dorsal limb structures, the glomerular basement membrane, the anterior segment of the eye, and dopaminergic and serotonergic neurons. Mutations in this gene are associated with nail-patella syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010],