LIPA2 rabbit pAb

SKU: ES15155

Size: 100μL

Source:Rabbit

Applications:WB;ELISA;IHC

Reactivity:Human; Mouse

Dilution:WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000

Immunogen:Synthesized peptide derived from human LIPA2 AA range: 49-99

Storage_stability:-20°C/1 year

Clonality:Polyclonal

Isotype:IgG

Concentration:1 mg/ml

Observed_band(KD):

Human_gene_id:8499

Human_swiss_prot_no:O75334

Subcellular_location:Cytoplasm . Cell surface . Cell projection, dendritic spine . Colocalizes with PTPRF at the cell surface.

Other_name:

Background:The protein encoded by this gene is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. It has been proposed that liprins are multivalent proteins that form complex structures and act as scaffolds for the recruitment and anchoring of LAR family of tyrosine phosphatases. This protein has been shown to bind the calcium/calmodulin-dependent serine protein kinase (MAGUK family) protein (also known as CASK) and proposed to regulate higher-order brain functions in mammals. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013],