LIN7A Antibody, Biotin conjugated - Cat. #: CSB-PA012963LD01HU

SKU: CSB-PA012963LD01HU

Size :50ug

Clone Number:

Aliases:hLin-7 antibody; Lin 7 homolog A (C. elegans) antibody; LIN 7A antibody; Lin-7A antibody; LIN7 antibody; LIN7A antibody; LIN7A_HUMAN antibody; MALS-1 antibody; Mammalian LIN 7 1 antibody; Mammalian lin-seven protein 1 antibody; Protein lin-7 homolog A antibody; Tax interaction protein 33 antibody; TIP-33 antibody; Veli-1 antibody; VELI1 antibody; Vertebrate lin-7 homolog 1 antibody; Vertebrate LIN7 homolog 1 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:O14910

Immunogen:Recombinant Human Protein lin-7 homolog A protein (1-233AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA

Background:Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells. Forms membrane-associated multiprotein complexes that may regulate delivery and recycling of proteins to the correct membrane domains. The tripartite complex composed of LIN7 (LIN7A, LIN7B or LIN7C), CASK and APBA1 may have the potential to couple synaptic vesicle exocytosis to cell adhesion in brain. Ensures the proper localization of GRIN2B (subunit 2B of the NMDA receptor) to neuronal postsynaptic density and may function in localizing synaptic vesicles at synapses where it is recruited by beta-catenin and cadherin. Required to localize Kir2 channels, GABA transporter (SLC6A12) and EGFR/ERBB1, ERBB2, ERBB3 and ERBB4 to the basolateral membrane of epithelial cells.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:Biotin

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:LIN7A

Research Areas:Neuroscience; Signal transduction