Leptin/LEP Monoclonal Antibody

SKU: AN200097P

Size::

Storage:This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Monoclonal Antibodies

Abbreviation:LEP

Target Synonym:LEP;LEPD;OB;OBS;leptin;Obesity Homolog;Obese protein;Obesity factor;FLJ94114;homolog of;Leptin (murine obesity homolog);Leptin (obesity homolog;Leptin Murine Obesity Homolog;Leptin Precursor Obesity Factor;mouse;mouse);Obese;Obesity;Obesity homolog mouse;Obesity Murine Homolog Leptin;OTTHUMP00000212285

Research Areas:Signal Transduction;Neuroscience;Stem Cells;Cardiovascular;Metabolism

Conjugation:Unconjugated

Host:Mouse

Species reactivity:Human

Application:WB

Isotype:IgG1

Clonality:Monoclonal

Clone NO.:9B9

UNIProt ID:P41159

Accession:

Background:Leptin is a protein product of the mouse obese gene. Mice with mutations in the obese gene that block the sythesis of Leptin have been found to be obese, diabetic and to have reduced activity, metabolism and body temperature. cDNA clones encoding Leptin have been isolated from human, simian, mouse and rat cells. Human Leptin shares approximately 84% sequence identity with the mouse protein. Human Leptin cDNA encodes a 167 amino acid residue protein with a 21 amino acid residue signal sequence that is cleaved to yield the 146 amino acid residue mature protein. The expression of Leptin mRNA has been shown to be restricted to adipose tissue.

Concentration:1 mg/mL

Immunogen:Recombinant Human Leptin protein

Buffer:0.2 μm filtered solution in PBS

Purification method:Protein A

Dilution:WB 1:500-1:1000;

Calculated MW:16 kDa

ObservedMW:14 kDa