LDHA Polyclonal Antibody

SKU: D-AB-10210L

Size::25μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Polyclonal Antibodies

Abbreviation:LDHA

Target Synonym:Cell proliferation-inducing gene 19 protein; GSD11; L lactate dehydrogenase A chain; l7R2; LDH M; LDH muscle subunit; LDH1; PIG19 Proliferation-inducing gene 19

Research Areas:Cancer;Metabolism;Signal Transduction

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:WB;IHC

Isotype:IgG

Clonality:Polyclonal

Clone NO.:

UNIProt ID:P00338

Accession:

Background:LDHA,also named as LDH-M and NY-REN-59,is an enzyme which catalyzes the inter-conversion of pyruvate and L-lactate with concomitant inter-conversion of NADH and NAD+. LDHA is found in most somatic tissues,though predominantly in muscle tissue and tumours,and belongs to the lactate dehydrogenase family. It has long been known that many human cancers have higher LDHA levels compared to normal tissues. It has also been shown that LDHA plays an important role in the development,invasion and metastasis of malignancies. Mutations in LDHA have been linked to exertional myoglobinuria. LDHA has some isoforms with MW 26-40 kDa.

Concentration:1 mg/mL

Immunogen:Recombinant Human LDHA protein expressed by E.coli

Buffer:PBS with 0.02% sodium azide,1% protective protein and 50% glycerol,pH7.4

Purification method:Antigen Affinity Purification

Dilution:WB 1:2500-1:5000;IHC 1:200-1:400

Calculated MW:26,30,36,39 kDa

ObservedMW:36 kDa