LASP-1 rabbit pAb

SKU: ES3964

Size: 100μL

Source:Rabbit

Applications:WB;IHC

Reactivity:Human;Mouse;Rat

Dilution:WB 1:500-2000;IHC-p 1:50-300

Immunogen:The antiserum was produced against synthesized peptide derived from the Internal region of human LASP1. AA range:51-100

Storage_stability:-20°C/1 year

Clonality:Polyclonal

Isotype:IgG

Concentration:1 mg/ml

Observed_band(KD):28kD

Human_gene_id:3927

Human_swiss_prot_no:Q14847

Subcellular_location:Cytoplasm, cell cortex . Cytoplasm, cytoskeleton . Associated with the F-actin rich cortical cytoskeleton. .

Other_name:LASP1; MLN50; LIM and SH3 domain protein 1; LASP-1; Metastatic lymph node gene 50 protein; MLN 50

Background:This gene encodes a member of a subfamily of LIM proteins, characterized by a LIM motif and a domain of Src homology region 3, and also a member of the nebulin family of actin-binding proteins. The encoded protein is a cAMP and cGMP dependent signaling protein and binds to the actin cytoskeleton at extensions of the cell membrane. The encoded protein has been linked to metastatic breast cancer, hematopoetic tumors such as B-cell lymphomas, and colorectal cancer. [provided by RefSeq, Oct 2012],