Lamin B1 Rabbit pAb

SKU: EA041

Size: 100μL

Source:Rabbit

Applications:WB, IHC

Reactivity:Human, Rat, Mouse

Dilution:WB 1:1,000-3,000 IHC: 1:500-1,000

Immunogen:Recombinant Protein

Storage_stability:PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Clonality:Polyclonal

Isotype:IgG

Concentration:1mg/mL

Observed_band(KD):68,45kDa

Human_gene_id:4001

Human_swiss_prot_no:P20700

Subcellular_location:Mitochondrion inner membrane

Other_name:ADLD, LMB1,LMNB1, MGC111419, OTTHUMP00000159218

Background:The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. This gene encodes one of the two B type proteins, B1.