KRAS antibody , Cat. # FNab04641

SKU: FNab04641

Size:100ug

Purification:Immunogen affinity purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Rabbit

Clonality:polyclonal

Clone ID:

Isotype:IgG

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays an important role in the regulation of cell proliferation(PubMed:23698361, PubMed:22711838). Plays a role in promoting oncogenic events by inducing transcriptional silencing of tumor suppressor genes(TSGs) in colorectal cancer(CRC) cells in a ZNF304-dependent manner(PubMed:24623306).

Immunogen:v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog

Synonyms:C K RAS, c Ki ras, GTPase KRas, K Ras 2, K RAS2A, K RAS2B, K RAS4A, K RAS4B, KI RAS, KRAS, KRAS1, KRAS2, KRAS2B speicifc, Krasa, Krasb, NS3, RASK2

Observed MW:21 kDa

Uniprot ID:P01116

Reactivity:Human, Mouse, Rat

Tested Application:ELISA, WB, IP, IHC

Recommended dilution:WB: 1:500 - 1:1000; IHC: 1:50 - 1:200; IP: 1:50 - 1:200

Gene ID:3845

Research Area:Cancer, Immunology, Signal Transduction, Cell Division and Proliferation