Ki67 Monoclonal Antibody

SKU: BT-MCA4777

Size:100μL

Background:Ki67: antigen identified by monoclonal antibody Ki-67. Ki67 antigen is the prototypic cell cycle related nuclear protein, expressed by proliferating cells in all phases of the active cell cycle (G1, S, G2 and M phase). It is absent in resting (G0) cells. Ki67 antibodies are useful in establishing the cell growing fraction in neoplasms (immunohistochemically quantified by determining the number of Ki67 positive cells among the total number of resting cells = Ki67 index). In neoplastic tissues the prognostic value is comparable to the tritiated thymidine labelling index. The correlation between low Ki67 index and histologically low grade tumours is strong. Ki67 is routinely used as a neuronal marker of cell cycling and proliferation.

Research_area:Others

Target_protein:Ki67

applications:

Reactivity:Human

Clonality:Monoclonal

Clone ID:9C12B2

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:Ki67

Immunogen:Purified recombinant fragment of Ki167 (aa3118-3256) expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Ascitic fluid containing 0.03% sodium azide.

Concentration:

Molecular weight(Da):358kDa

UniProt accession:P46013

Synonyms:KIA, Ki-67, MKI67

GeneID:4288