KCNIP3 Polyclonal Antibody

SKU: E-AB-19200

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: KCNIP3

Target Synonym: 4933407H12Rik;A type potassium channel modulatory protein 3;A-type potassium channel modulatory protein 3;AI413860;Calsenilin;CSEN;CSEN;DRE antagonist modulator;DRE-antagonist modulator;DREAM;EF hand transcription factor;KCHIP 3;KChIP3;KCNIP 3;Kcnip3;Kv channel interacting protein 3;Kv channel-interacting protein 3;MGC18289;Potassium channel interacting protein 3;R74849

Research Areas: Cancer;Cardiovascular;Neuroscience;Signal Transduction

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human;Mouse;Rat

Application: IHC

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: Q9Y2W7

Accession:

Background: This gene encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins, which belong to the recoverin branch of the EF-hand superfamily. Members of this family are small calcium binding proteins containing EF-hand-like domains. They are integral subunit components of native Kv4 channel complexes that may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. The encoded protein also functions as a calcium-regulated transcriptional repressor, and interacts with presenilins. Alternatively spliced transcript variants encoding different isoforms have been described. KCNIP3 (Potassium Voltage-Gated Channel Interacting Protein 3) is a Protein Coding gene. Diseases associated with KCNIP3 include Alzheimer Disease. Among its related pathways are Cardiac conduction and Development Ligand-independent activation of ESR1 and ESR2. GO annotations related to this gene include calcium ion binding and transcription corepressor activity. An important paralog of this gene is KCNIP4.

Concentration: 1.62 mg/mL

Immunogen: Fusion protein of human KCNIP3

Buffer: PBS with 0.05% NaN3 and 40% Glycerol,pH7.4

Purification method: Antigen affinity purification

Dilution: IHC 1:50-1:100

Calculated MW:

ObservedMW: