KCNE3 rabbit pAb

SKU: ES10028

Size: 100μL

Source:Rabbit

Applications:WB;ELISA

Reactivity:Human;Mouse;Rat

Dilution:WB 1:500-2000 ELISA 1:5000-20000

Immunogen:Synthesized peptide derived from human protein . at AA range: 30-110

Storage_stability:-20°C/1 year

Clonality:Polyclonal

Isotype:IgG

Concentration:1 mg/ml

Observed_band(KD):11kD

Human_gene_id:10008

Human_swiss_prot_no:Q9Y6H6

Subcellular_location:Cell membrane ; Single-pass type I membrane protein . Cytoplasm . Perikaryon . Cell projection, dendrite . Membrane raft . Colocalizes with KCNB1 at high-density somatodendritic clusters on the surface of hippocampal neurons. .

Other_name:

Background:potassium voltage-gated channel subfamily E regulatory subunit 3(KCNE3) Homo sapiens Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, isk-related subfamily. This member is a type I membrane protein, and a beta subunit that assembles with a potassium channel alpha-subunit to modulate the gating kinetics and enhance stability of the multimeric complex. This gene is prominently expressed in the kidney. A missense mutation in this gene is associated with hypokalemic periodic paralysis. [provided by RefSeq, Jul 2008],