ITGB7 Monoclonal Antibody

SKU: BT-MCA4031

Size:100μL

Background:This gene encodes a protein that is a member of the integrin superfamily. Members of this family are adhesion receptors that function in signaling from the extracellular matrix to the cell. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. The encoded protein forms dimers with an alpha4 chain or an alphaE chain and plays a role in leukocyte adhesion. Dimerization with alpha4 forms a homing receptor for migration of lymphocytes to the intestinal mucosa and Peyer's patches. Dimerization with alphaE permits binding to the ligand epithelial cadherin, a calcium-dependent adhesion molecule. Alternate splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.

Research_area:Signal transduction, Stem cells, Immunology

Target_protein:ITGB7

applications:IHC, ICC, FCM

Reactivity:Human

Clonality:Monoclonal

Clone ID:6A2G4

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:ITGB7

Immunogen:Purified recombinant fragment of human ITGB7 (AA: 20-174) expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Purified antibody in PBS with 0.05% sodium azide

Concentration:

Molecular weight(Da):86.9kDa

UniProt accession:P26010

Synonyms:

GeneID:3695