ITGAV Rabbit Polyclonal Antibody

SKU: BT-AP03164

Size:100μL

Background:The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha V subunit. This subunit associates with beta 1| beta 3| beta 5| beta 6 and beta 8 subunits. The heterodimer consisting of alpha V and beta 3 subunits is also known as the vitronectin receptor. This integrin may regulate angiogenesis and cancer progression. Alternative splicing results in multiple transcript variants. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes.

Research_area:Cardiovascular; Stem cells; Microbiology; Signal transduction; Immunology; Cancer

Target_protein:ITGAV

applications:WB, ELISA

Reactivity:Human, Mouse

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:ITGAV

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):115280

UniProt accession:Human: P06756; Mouse: P43406

Synonyms:ITGAV ;light chain; Cleaved-Asp891; Integrin alpha-V; Vitronectin receptor subunit alpha; CD antigen CD51; Integrin alpha-V heavy chain; Integrin alpha-V light chain;

GeneID:Human: 3685; Mouse: 16410