ISCU Polyclonal Antibody

SKU: E-AB-18785

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: ISCU

Target Synonym: 2310020H20Rik;HML;hnifU;Iron sulfur cluster assembly enzyme ISCU mitochondrial;Iron sulfur cluster scaffold homolog (E. coli);Iron sulfur cluster scaffold homolog;Iron-sulfur cluster assembly enzyme ISCU;Iscu;IscU iron sulfur cluster scaffold homolog;ISCU;ISU2;MGC74517;mitochondrial;NIFU;NifU like N terminal domain containing;NifU like N terminal domain containing protein;NifU like protein;NifU-like N-terminal domain-containing protein;NifU-like protein;NIFUN;Nitrogen fixation cluster like;OTTHUMP00000238760;OTTHUMP00000238761;OTTHUMP00000238762;OTTHUMP00000238764;OTTHUMP00000238765

Research Areas: Metabolism;Signal transduction

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human;Mouse

Application: WB

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: Q9H1K1

Accession:

Background: This gene encodes a component of the iron-sulfur (Fe-S) cluster scaffold. Fe-S clusters are cofactors that play a role in the function of a diverse set of enzymes, including those that regulate metabolism, iron homeostasis, and oxidative stress response. Alternative splicing results in transcript variants encoding different protein isoforms that localize either to the cytosol or to the mitochondrion. Mutations in this gene have been found in patients with hereditary myopathy with lactic acidosis. A disease-associated mutation in an intron may activate a cryptic splice site, resulting in the production of a splice variant encoding a putatively non-functional protein. A pseudogene of this gene is present on chromosome 1.

Concentration: 0.96 mg/mL

Immunogen: Fusion protein of human ISCU

Buffer: PBS with 0.05% NaN3 and 40% Glycerol,pH7.4

Purification method: Antigen affinity purification

Dilution: WB 1:500-1:2000

Calculated MW: 18 kDa

ObservedMW: Refer to figures