IRF-3(Phospho Ser385) Polyclonal Antibody

SKU: BT-AP10486

Size:100μL

Background:This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Research_area:Epigenetics and nuclear signaling; Immunology ; Microbiology

Target_protein:IRF3

applications:WB, IHC-p, IF, ICC, ELISA

Reactivity:Human, Rat, Mouse

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:Interferon regulatory factor 3

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):47219

UniProt accession:Human: Q14653; Mouse: P70671

Synonyms:Interferon regulatory factor 3; IRF3; Interferon regulatory factor 3; IRF-3

GeneID:Human: 3661