InVivoMAb Anti-Mouse GIPR/GIP-R (Iv0037)

SKU: MW595010

Size:100ug

Description:GIPR is a key metabolic regulator involved in nutrient sensing and energy balance. Iv0037 is a potent, fully antagonistic anti-mouse GIPR monoclonal antibody that locks the receptor’s extracellular domain in a unique auto-inhibitory conformation. By partially blocking ligand binding and mimicking the receptor’s C-terminal stalk, Iv0037 stabilizes GIPR in a novel inhibited state. In diet-induced obese mice, Iv0037 treatment reduces body-weight gain and improves metabolic profiles.

Host species:Mouse

Species reactivity:Mouse

Form:Liquid

Storage buffer:0.01M PBS, pH 7.4.

Purity:>95% as determined by SDS-PAGE.

Clonality:Monoclonal

Isotype:IgG2a, kappa

Applications:ELISA, Neutralization

Target:Gastric inhibitory polypeptide receptor, GIP-R, Glucose-dependent insulinotropic polypeptide receptor, Gipr

Purification:Protein A/G purified from cell culture supernatant.

Endotoxin level:Please contact us for this information.

Accession:Q0P543

Stability and Storage:Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID:Iv0037

Product Usage Information:

Predicted molecular weight:

Note:For research use only. Not suitable for clinical or therapeutic use.