Integrin alphaIIb Rabbit Polyclonal Antibody

SKU: BT-AP10615

Size:100μL

Background:This gene encodes a member of the integrin alpha chain family of proteins. The encoded preproprotein is proteolytically processed to generate light and heavy chains that associate through disulfide linkages to form a subunit of the alpha-IIb/beta-3 integrin cell adhesion receptor. This receptor plays a crucial role in the blood coagulation system| by mediating platelet aggregation. Mutations in this gene are associated with platelet-type bleeding disorders| which are characterized by a failure of platelet aggregation| including Glanzmann thrombasthenia.

Research_area:Cardiovascular; Immunology; Signal transduction; Stem cells

Target_protein:ITGA2B

applications:WB, ELISA

Reactivity:Human, Rat, Mouse

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:Integrin alpha IIb

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):114290

UniProt accession:Human: P08514; Mouse: Q9QUM0

Synonyms:Integrin αIIb; Integrin alpha-IIb; GPalpha IIb; GPIIb; Platelet membrane glycoprotein IIb; CD antigen CD41; Integrin alpha-IIb heavy chain; Integrin alpha-IIb light chain; form 1; Integrin alpha-IIb light chain; form 2;

GeneID:Human: 3674; Mouse: 16399