IMPDH2 Antibody - Cat. #: CSB-PA914299

SKU: CSB-PA914299

Size :50ul

Clone Number:

Aliases:IMDH2_HUMAN antibody; IMP (inosine monophosphate) dehydrogenase 2 antibody; IMP dehydrogenase 2 antibody; IMP oxireductase 2 antibody; IMPD 2 antibody; IMPD2 antibody; IMPDH 2 antibody; IMPDH II antibody; IMPDH-II antibody; Impdh2 antibody; Inosine 5' monophosphate dehydrogenase 2 antibody; Inosine 5' phosphate dehydrogenase 2 antibody; Inosine monophosphate dehydrogenase type II antibody; Inosine-5''-monophosphate dehydrogenase 2 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P12268

Immunogen:Fusion protein of Human IMPDH2

Raised in:Rabbit

Species Reactivity:Human, Mouse, Rat

Tested Applications:ELISA, WB, IHC; ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:50-1:200

Background:This gene encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. The encoded protein catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. This gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:IMPDH2

Research Areas:Cancer;Metabolism;Signal transduction