ILK Monoclonal Antibody

SKU: BT-MCA4526

Size:100μL

Background:Transduction of extracellular matrix signals through integrins influences intracellular and extracellular functions, and appears to require interaction of integrin cytoplasmic domains with cellular proteins. Integrin-linked kinase (ILK), interacts with the cytoplasmic domain of beta-1 integrin. This gene encodes a serine/threonine protein kinase with 4 ankyrin-like repeats, which associates with the cytoplasmic domain of beta integrins and acts as a proximal receptor kinase regulating integrin-mediated signal transduction. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene.

Research_area:Signal Transduction

Target_protein:ILK

applications:WB, IHC, FCM

Reactivity:Human, Mouse, Monkey

Clonality:Monoclonal

Clone ID:3A9

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:ILK

Immunogen:Purified recombinant fragment of human ILK (AA: 97-244) expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Ascitic fluid containing 0.03% sodium azide.

Concentration:

Molecular weight(Da):51.4kDa

UniProt accession:Q13418

Synonyms:P59, ILK-2

GeneID:3611