IL-19 rabbit pAb

SKU: ES8710

Size: 100μL

Source:Rabbit

Applications:WB;IHC;IF;ELISA

Reactivity:Human;Rat

Dilution:WB 1:500-2000,IHC-p 1:500-200, ELISA 1:10000-20000

Immunogen:Synthetic peptide from human protein at AA range: 51-100

Storage_stability:-20°C/1 year

Clonality:Polyclonal

Isotype:IgG

Concentration:1 mg/ml

Observed_band(KD):20kD

Human_gene_id:29949

Human_swiss_prot_no:Q9UHD0

Subcellular_location:Secreted.

Other_name:Interleukin-19 (IL-19;Melanoma differentiation-associated protein-like protein;NG.1)

Background:The protein encoded by this gene is a cytokine that belongs to the IL10 cytokine subfamily. This cytokine is found to be preferentially expressed in monocytes. It can bind the IL20 receptor complex and lead to the activation of the signal transducer and activator of transcription 3 (STAT3). A similar cytokine in mouse is reported to up-regulate the expression of IL6 and TNF-alpha and induce apoptosis, which suggests a role of this cytokine in inflammatory responses. Alternatively spliced transcript variants encoding the distinct isoforms have been described. [provided by RefSeq, Jul 2008],