GeneBio Systems
IKBIP Polyclonal Antibody
IKBIP Polyclonal Antibody
SKU:E-AB-15128
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Size: 200μL
Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
Exp date: 12 months
Category ID_II: Primary Antibodies
Category ID_III: Polyclonal Antibodies
Abbreviation: IKBIP
Target Synonym: FLJ31051;I kappa B kinase interacting protein;IKBIP;IKBKB interacting protein;IKIP1;IKIP2;IKIP3;IKK interacting protein;Inhibitor of nuclear factor kappa B kinase interacting protein
Research Areas: Cancer;Cell Biology
Conjugation: Unconjugated
Host: Rabbit
Species reactivity: Human;Mouse;Rat
Application: IHC
Isotype: IgG
Clonality: Polyclonal
Clone NO.:
UNIProt ID: Q70UQ0
Accession:
Background: IKIP (Inhibitor of nuclear factor kappa-B kinase-interacting protein, IKK-interacting protein) is a single-pass membrane protein that shares a common promoter with APAF1. APAF1 and IKIP are both induced by X irradiation, however, the two gene products are transcribed in different directions. The IKIP gene is believed to be a target for p53 as expression of IKIP has been shown to promote apoptosis. IKIP has four known isoforms, three of which are found traversing the endoplasmic reticulum membrane. IKIP isoform 4 has a deletion of the transmembrane region which leads to a homogenous distribution of the protein within the cell. The IKIP gene products are expressed in vascular endothelial cells, while the isoform 4 has also been detected in lung, kidney, spleen, thymus and skeletal muscle.
Concentration: 0.4 mg/mL
Immunogen: Recombinant protein of human IKBIP
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification method: Affinity purification
Dilution: IHC 1:50-1:200
Calculated MW:
ObservedMW:
