IKBIP Antibody - Cat. #: CSB-PA505319

SKU: CSB-PA505319

Size :50ul

Clone Number:

Aliases:IKBIP antibody; IKIP antibody; Inhibitor of nuclear factor kappa-B kinase-interacting protein antibody; I kappa-B kinase-interacting protein antibody; IKBKB-interacting protein antibody; IKK-interacting protein antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q70UQ0

Immunogen:Fusion protein of Human IKBIP

Raised in:Rabbit

Species Reactivity:Human, Mouse, Rat

Tested Applications:ELISA, IHC; ELISA:1:2000-1:5000, IHC:1:50-1:200

Background:IKIP (Inhibitor of nuclear factor kappa-B kinase-interacting protein, IKK-interacting protein) is a single-pass membrane protein that shares a common promoter with APAF1. APAF1 and IKIP are both induced by X irradiation, however, the two gene products are transcribed in different directions. The IKIP gene is believed to be a target for p53 as expression of IKIP has been shown to promote apoptosis. IKIP has four known isoforms, three of which are found traversing the endoplasmic reticulum membrane. IKIP isoform 4 has a deletion of the transmembrane region which leads to a homogenous distribution of the protein within the cell. The IKIP gene products are expressed in vascular endothelial cells, while the isoform 4 has also been detected in lung, kidney, spleen, thymus and skeletal muscle.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:IKBIP

Research Areas:Cancer;Cell biology