IkB α Rabbit pAb

SKU: EA339

Size: 100μL

Source:Rabbit

Applications:WB, IHC

Reactivity:Human, Mouse, Rat

Dilution:WB 1:500-1,000 IHC 1:100-200

Immunogen:Recombinant Protein

Storage_stability:PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Clonality:Polyclonal

Isotype:IgG

Concentration:1mg/mL

Observed_band(KD):40kDa

Human_gene_id:4792

Human_swiss_prot_no:P25963

Subcellular_location:Cytoplasm, Nucleus

Other_name:I kappa B alpha antibody, IkB-alpha antibody, IKBA antibody, MAD3 antibody, NFKB inhibitor antibody

Background:Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. IκBα phosphorylation and resulting Rel-dependent transcription are activated by a highly diverse group of extracellular signals including inflammatory cytokines, growth factors, and chemokines.