HYAL2 Antibody - Cat. #: CSB-PA014449

SKU: CSB-PA014449

Size :50ul

Clone Number:

Aliases:Hyal 2 antibody; Hyal-2 antibody; Hyal2 antibody; HYAL2_HUMAN antibody; Hyaluronidase 2 antibody; Hyaluronidase 2 Precursor antibody; Hyaluronidase-2 antibody; Hyaluronoglucosaminidase 2 antibody; Hyaluronoglucosaminidase-2 antibody; LUCA 2 antibody; LUCA-2 antibody; LUCA2 antibody; Lung carcinoma protein 2 antibody; lysosomal hyaluronidase antibody; PH 20 homolog antibody; PH-20 homolog antibody; PH20 homolog antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q12891

Immunogen:Fusion protein of Human HYAL2

Raised in:Rabbit

Species Reactivity:Human, Mouse, Rat

Tested Applications:ELISA, IHC; ELISA:1:2000-1:5000, IHC:1:50-1:200

Background:This gene encodes a weak acid-active hyaluronidase. The encoded protein is similar in structure to other more active hyaluronidases. Hyaluronidases degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. Hyaluronan and fragments of hyaluronan are thought to be involved in cell proliferation, migration and differentiation. Although it was previously thought to be a lysosomal hyaluronidase that is active at a pH below 4, the encoded protein is likely a GPI-anchored cell surface protein. This hyaluronidase serves as a receptor for the oncogenic virus Jaagsiekte sheep retrovirus. The gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression. This gene encodes two alternatively spliced transcript variants which differ only in the 5' UTR.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:HYAL2

Research Areas:Cancer;Signal transduction