HUWE1 Polyclonal Antibody

SKU: E-AB-19540

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: HUWE1

Target Synonym: ARF binding protein 1;ARF BP1;ARF-binding protein 1;ARF-BP1;BJ-HCC-24 tumor antigen;E3 ubiquitin protein ligase HUWE1;E3 ubiquitin-protein ligase HUWE1;HECT;HECT domain protein LASU1;HECT UBA and WWE domain containing protein 1;HectH9;Homologous to E6AP carboxyl terminus homologous protein 9;Huwe1;HUWE1;Ib772;Large structure of UREB1;LASU1;Mcl 1 ubiquitin ligase E3;Mcl-1 ubiquitin ligase E3;Mule;UBA and WWE domain-containing protein 1;Upstream regulatory element-binding protein 1;URE-B1;URE-binding protein 1;UREB1

Research Areas: Cancer;Cell Biology

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human;Mouse;Rat

Application: IHC

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: Q7Z6Z7

Accession:

Background: This gene encodes a protein containing a C-terminal HECT (E6AP type E3 ubiquitin protein ligase) domain that functions as an E3 ubiquitin ligase. The encoded protein is required for the ubiquitination and subsequent degradation of the anti-apoptotic protein Mcl1 (myeloid cell leukemia sequence 1 (BCL2-related)). This protein also ubiquitinates the p53 tumor suppressor, core histones, and DNA polymerase beta. Mutations in this gene are associated with Turner type X-linked syndromic mental retardation.

Concentration: 0.8 mg/mL

Immunogen: Synthetic peptide of human HUWE1

Buffer: PBS with 0.05% NaN3 and 40% Glycerol,pH7.4

Purification method: Antigen affinity purification

Dilution: IHC 1:10-1:50

Calculated MW:

ObservedMW: